Ticker · CUSIP 90240B106

TYRA

TYRA BIOSCIENCES INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

1,284,271

Combined value

$33.76M

Last close

$35.56

Quarter

2025Q4

Price is +35.3% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$35.56+26.64 (+298.65%)H $39.61 · L $8.82 · Avg Vol 516K

Position opened

Tracked holders · last 8 quarters

-1 vs previous quarter over the last 8.

SEC event timeline

17 events

AQR Capital Management added2026-02-17
+562 shares · 2025Q4
Position
Two Sigma Investments trimmed2026-02-17
−92,415 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) trimmed2026-02-17
−29,628 shares · 2025Q4
Position
Steve Cohen (Point72) added2026-02-17
+592,160 shares · 2025Q4
Position
T. Rowe Price added2026-02-17
+1,631 shares · 2025Q4
Position
Wellington Management added2026-02-17
+21,434 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) exited2026-02-17
−111,293 shares · 2025Q4
Position
Renaissance Technologies exited2026-02-12
−170,100 shares · 2025Q4
Position
Ken Fisher (Fisher Asset Mgmt) opened position2026-02-09
+28,800 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) exited2025-12-09
−26,265 shares · 2025Q3
Position
Steve Cohen (Point72) added2025-11-14
+57,332 shares · 2025Q3
Position
Two Sigma Investments added2025-11-14
+93,613 shares · 2025Q3
Position
T. Rowe Price added2025-11-14
+779 shares · 2025Q3
Position
Wellington Management trimmed2025-11-14
−20,207 shares · 2025Q3
Position
AQR Capital Management trimmed2025-11-14
−643 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−263,448 shares · 2025Q3
Position
Renaissance Technologies added2025-11-13
+35,000 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for TYRA →

Follow-the-investor returns

If you'd copied each holder of TYRA…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Ken Griffin (Citadel Advisors)	2022Q1	$9.57	+271.6%	$445K
AQR Capital Management	2025Q2	$9.90	+259.3%	$1.0M
T. Rowe Price	2025Q2	$11.77	+202.1%	$513K
Izzy Englander (Millennium Mgmt)	2021Q3	$12.94	+174.8%	$4.1M
Two Sigma Investments	2024Q1	$13.25	+168.3%	$3.8M
Wellington Management	2021Q3	$16.82	+111.5%	$3.7M
Steve Cohen (Point72)	2024Q4	$21.24	+67.4%	$31.1M
Ken Fisher (Fisher Asset Mgmt)	2025Q4	$26.29	+35.3%	$1.0M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions1

Ken Fisher (Fisher Asset Mgmt)
+28,800
$757K

Added to4

Steve Cohen (Point72)
+592,160
$15.6M
Wellington Management
+21,434
$563K
AQR Capital Management
+562
$15K
T. Rowe Price
+1,631
$43

Trimmed2

Two Sigma Investments
−92,415
$2.4M
Izzy Englander (Millennium Mgmt)
−29,628
$779K

Exited2

Renaissance Technologies
−170,100
$2.4M
Ken Griffin (Citadel Advisors)
−111,293
$1.6M

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	5	1,025,505	$11.0M	—
2022Q2	4	816,618	$5.8M	-1
2022Q3	4	782,785	$6.9M	—
2022Q4	6	798,068	$6.1M	+2
2023Q1	3	764,620	$12.3M	-3
2023Q2	3	991,859	$16.9M	—
2023Q3	1	896,452	$12.3M	-2
2023Q4	1	965,034	$13.4M	—
2024Q1	7	1,263,244	$20.7M	+6
2024Q2	3	1,571,159	$25.1M	-4
2024Q3	8	245,506	$5.8M	+5
2024Q4	8	484,257	$6.7M	—
2025Q1	9	802,045	$7.5M	+1
2025Q2	9	1,259,302	$12.1M	—
2025Q3	9	1,054,120	$14.7M	—
2025Q4	8	1,284,271	$33.8M	-1

Who owns TYRA

8 super-investors · 2025Q4

Tracked stake

1.28M

Combined value

$34M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New1Added4Trim2Sold1

#	Manager	Shares	Value	% of book	Last action	8Q trend
1	Steve Cohen Point72	874.2K	$23M	0.0%	Added+592.2K
2	Izzy Englander Millennium Mgmt	114.4K	$3M	0.0%	Trim−29.6K
3	Two Sigma Investments	107.0K	$3M	0.0%	Trim−92.4K
4	Wellington Management	104.3K	$3M	0.0%	Added+21.4K
5	Ken Fisher Fisher Asset Mgmt	28.8K	$757K	0.0%	New+28.8K	—
6	AQR Capital Management	28.6K	$753K	0.0%	Added+562
7	T. Rowe Price	14.4K	$380K	0.0%	Added+1.6K
8	Ken Griffin Citadel Advisors	12.5K	$329K	0.0%	Sold−111.3K

Recent moves

20 transactions

ADDWellington Management
+21,434 · 2025Q4
ADDT. Rowe Price
+1,631 · 2025Q4
ADDAQR Capital Management
+562 · 2025Q4
TRIMTwo Sigma Investments
−92,415 · 2025Q4
ADDSteve Cohen (Point72)
+592,160 · 2025Q4
TRIMIzzy Englander (Millennium Mgmt)
−29,628 · 2025Q4
SOLDKen Griffin (Citadel Advisors)
−111,293 · 2025Q4
SOLDRenaissance Technologies
−170,100 · 2025Q4
NEWKen Fisher (Fisher Asset Mgmt)
+28,800 · 2025Q4
SOLDPaul Tudor Jones (Tudor Investment)
−26,265 · 2025Q3
ADDTwo Sigma Investments
+93,613 · 2025Q3
ADDT. Rowe Price
+779 · 2025Q3
ADDSteve Cohen (Point72)
+57,332 · 2025Q3
TRIMWellington Management
−20,207 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−263,448 · 2025Q3
TRIMAQR Capital Management
−643 · 2025Q3
ADDRenaissance Technologies
+35,000 · 2025Q3
ADDTwo Sigma Investments
+41,007 · 2025Q2
ADDIzzy Englander (Millennium Mgmt)
+3,299 · 2025Q2
ADDSteve Cohen (Point72)
+175,100 · 2025Q2

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