Ticker · CUSIP 76243J105

RYTM

RHYTHM PHARMACEUTICALS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

3,127,162

Combined value

$334.73M

Last close

$88.69

Quarter

2025Q4

Price is -17.1% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$88.69+26.95 (+43.65%)H $117.62 · L $56.79 · Avg Vol 733K

Tracked holders · last 8 quarters

Flat over the last 8 quarters.

SEC event timeline

19 events

D.E. Shaw & Co. added2026-02-17
+27,771 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) added2026-02-17
+20,696 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+53,548 shares · 2025Q4
Position
T. Rowe Price added2026-02-17
+160,950 shares · 2025Q4
Position
Wellington Management added2026-02-17
+225,679 shares · 2025Q4
Position
AQR Capital Management trimmed2026-02-17
−9,734 shares · 2025Q4
Position
Steve Cohen (Point72) opened position2026-02-17
+429,420 shares · 2025Q4
Position
Renaissance Technologies trimmed2026-02-12
−205,400 shares · 2025Q4
Position
Norges Bank (Norway SWF) opened position2026-02-10
+66,213 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) exited2025-12-09
−4,272 shares · 2025Q3
Position
AQR Capital Management added2025-11-14
+30,740 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−64,949 shares · 2025Q3
Position
Steve Cohen (Point72) exited2025-11-14
−170,832 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−20,693 shares · 2025Q3
Position
T. Rowe Price added2025-11-14
+58,505 shares · 2025Q3
Position
Wellington Management added2025-11-14
+2,052 shares · 2025Q3
Position
Renaissance Technologies added2025-11-13
+231,700 shares · 2025Q3
Position
Norges Bank (Norway SWF) exited2025-11-13
−207,389 shares · 2025Q3
Position
Norges Bank (Norway SWF) added2025-11-12
+23,038 shares · 2024Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for RYTM →

Follow-the-investor returns

If you'd copied each holder of RYTM…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Norges Bank (Norway SWF)	2017Q4	$48.92	+81.3%	$5.9M
T. Rowe Price	2017Q4	$55.87	+58.8%	$138.4M
AQR Capital Management	2021Q3	$69.90	+26.9%	$6.2M
Renaissance Technologies	2019Q3	$78.13	+13.5%	$30.3M
Steve Cohen (Point72)	2017Q4	$87.80	+1.0%	$38.1M
Wellington Management	2017Q4	$99.94	-11.3%	$22.2M
D.E. Shaw & Co.	2018Q2	$100.89	-12.1%	$2.8M
Izzy Englander (Millennium Mgmt)	2018Q2	$100.98	-12.2%	$16.6M
Ken Griffin (Citadel Advisors)	2017Q4	$106.74	-16.9%	$13.6M
Ken Griffin (Citadel Advisors)	2017Q4	$106.74	-16.9%	$13.6M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions2

Steve Cohen (Point72)
+429,420
$46.0M
Norges Bank (Norway SWF)
+66,213
$7.1M

Added to5

Wellington Management
+225,679
$24.2M
Izzy Englander (Millennium Mgmt)
+53,548
$5.7M
D.E. Shaw & Co.
+27,771
$3.0M
Ken Griffin (Citadel Advisors)
+20,696
$2.2M
T. Rowe Price
+160,950
$17K

Trimmed2

Renaissance Technologies
−205,400
$22.0M
AQR Capital Management
−9,734
$1.0M

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	10	4,370,086	$50.3M	—
2022Q2	8	2,309,222	$9.6M	-2
2022Q3	8	4,286,512	$105.0M	—
2022Q4	8	4,362,456	$127.0M	—
2023Q1	11	5,424,690	$96.8M	+3
2023Q2	8	6,866,904	$113.2M	-3
2023Q3	11	6,848,025	$157.0M	+3
2023Q4	8	7,179,975	$330.1M	-3
2024Q1	10	7,442,024	$322.5M	+2
2024Q2	7	7,678,859	$315.3M	-3
2024Q3	9	880,880	$46.2M	+2
2024Q4	9	1,166,679	$65.3M	—
2025Q1	12	1,794,057	$95.0M	+3
2025Q2	12	2,388,331	$150.9M	—
2025Q3	10	2,399,819	$242.4M	-2
2025Q4	10	3,127,162	$334.7M	—

Who owns RYTM

10 super-investors · 2025Q4

Tracked stake

3.13M

Combined value

$335M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New2Added6Trim2

#	Manager	Shares	Value	% of book	Last action
1	T. Rowe Price	1.56M	$167M	0.0%	Added+160.9K
2	Steve Cohen Point72	429.4K	$46M	0.1%	New+429.4K
3	Renaissance Technologies	341.2K	$37M	0.1%	Trim−205.4K
4	Wellington Management	250.2K	$27M	0.0%	Added+225.7K
5	Izzy Englander Millennium Mgmt	186.7K	$20M	0.0%	Added+53.5K
6	Ken Griffin Citadel Advisors	153.3K	$16M	0.0%	Added+20.7K
7	AQR Capital Management	70.0K	$7M	0.0%	Trim−9.7K
8	Norges Bank Norway SWF	66.2K	$7M	0.0%	New+66.2K
9	Ken Griffin Citadel Advisors	37.9K	$4M	0.0%	Added+20.7K
10	D.E. Shaw & Co.	31.4K	$3M	0.0%	Added+27.8K

Recent moves

20 transactions

ADDWellington Management
+225,679 · 2025Q4
TRIMAQR Capital Management
−9,734 · 2025Q4
ADDT. Rowe Price
+160,950 · 2025Q4
NEWSteve Cohen (Point72)
+429,420 · 2025Q4
ADDKen Griffin (Citadel Advisors)
+20,696 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+53,548 · 2025Q4
ADDD.E. Shaw & Co.
+27,771 · 2025Q4
TRIMRenaissance Technologies
−205,400 · 2025Q4
NEWNorges Bank (Norway SWF)
+66,213 · 2025Q4
SOLDPaul Tudor Jones (Tudor Investment)
−4,272 · 2025Q3
ADDAQR Capital Management
+30,740 · 2025Q3
SOLDSteve Cohen (Point72)
−170,832 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−64,949 · 2025Q3
ADDT. Rowe Price
+58,505 · 2025Q3
TRIMD.E. Shaw & Co.
−20,693 · 2025Q3
ADDWellington Management
+2,052 · 2025Q3
ADDRenaissance Technologies
+231,700 · 2025Q3
SOLDNorges Bank (Norway SWF)
−207,389 · 2025Q3
ADDNorges Bank (Norway SWF)
+23,038 · 2024Q3
ADDSteve Cohen (Point72)
+106,990 · 2025Q2

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