Ticker · CUSIP 682143102

OMER

OMEROS CORP

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

3,086,119

Combined value

$53.00M

Last close

$13.44

Quarter

2025Q4

Price is -21.7% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$13.44+6.66 (+98.23%)H $17.18 · L $2.97 · Avg Vol 2.0M

Tracked holders · last 8 quarters

-1 vs previous quarter over the last 8.

SEC event timeline

15 events

Ken Griffin (Citadel Advisors) trimmed2026-02-17
−152,876 shares · 2025Q4
Position
D.E. Shaw & Co. trimmed2026-02-17
−250,236 shares · 2025Q4
Position
Two Sigma Investments trimmed2026-02-17
−408,557 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+39,997 shares · 2025Q4
Position
T. Rowe Price added2026-02-17
+6,217 shares · 2025Q4
Position
Wellington Management added2026-02-17
+8,170 shares · 2025Q4
Position
AQR Capital Management added2026-02-17
+1,532 shares · 2025Q4
Position
Renaissance Technologies exited2026-02-12
−344,500 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2025-11-14
+132,393 shares · 2025Q3
Position
Two Sigma Investments added2025-11-14
+263,095 shares · 2025Q3
Position
AQR Capital Management added2025-11-14
+7,444 shares · 2025Q3
Position
Wellington Management added2025-11-14
+31,034 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−642,191 shares · 2025Q3
Position
T. Rowe Price added2025-11-14
+12,737 shares · 2025Q3
Position
Renaissance Technologies trimmed2025-11-13
−38,200 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for OMER →

Follow-the-investor returns

If you'd copied each holder of OMER…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Two Sigma Investments	2017Q2	$3.46	+288.9%	$7.1M
Wellington Management	2021Q4	$5.93	+126.5%	$2.7M
Izzy Englander (Millennium Mgmt)	2016Q1	$7.40	+81.7%	$5.9M
T. Rowe Price	2016Q3	$7.56	+77.7%	$1.3M
D.E. Shaw & Co.	2016Q1	$10.96	+22.6%	$10.1M
Ken Griffin (Citadel Advisors)	2016Q3	$10.99	+22.3%	$5.5M
Ken Griffin (Citadel Advisors)	2016Q3	$10.99	+22.3%	$5.5M
Ken Griffin (Citadel Advisors)	2016Q3	$10.99	+22.3%	$5.5M
AQR Capital Management	2017Q3	$11.90	+12.9%	$307K

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions0

—

Added to4

Izzy Englander (Millennium Mgmt)
+39,997
$687K
Wellington Management
+8,170
$140K
AQR Capital Management
+1,532
$26K
T. Rowe Price
+6,217
$107

Trimmed3

Two Sigma Investments
−408,557
$7.0M
D.E. Shaw & Co.
−250,236
$4.3M
Ken Griffin (Citadel Advisors)
−152,876
$2.6M

Exited1

Renaissance Technologies
−344,500
$1.4M

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	11	7,704,599	$46.3M	—
2022Q2	11	6,920,698	$19.0M	—
2022Q3	10	4,720,672	$14.9M	-1
2022Q4	10	4,411,034	$10.0M	—
2023Q1	9	3,432,905	$16.0M	-1
2023Q2	9	6,451,128	$35.1M	—
2023Q3	10	5,959,646	$17.4M	+1
2023Q4	7	4,576,702	$15.0M	-3
2024Q1	8	4,652,311	$16.1M	+1
2024Q2	9	6,124,544	$24.9M	+1
2024Q3	9	2,164,429	$8.6M	—
2024Q4	8	2,496,959	$24.7M	-1
2025Q1	9	3,021,551	$24.8M	+1
2025Q2	9	3,612,042	$10.8M	—
2025Q3	10	3,789,972	$15.5M	+1
2025Q4	9	3,086,119	$53.0M	-1

Who owns OMER

9 super-investors · 2025Q4

Tracked stake

3.09M

Combined value

$53M

% of shares outstanding

—

shares-out unknown

Quarter action mix

Added4Trim5

#	Manager	Shares	Value	% of book	Last action
1	D.E. Shaw & Co.	755.0K	$13M	0.0%	Trim−250.2K
2	Two Sigma Investments	524.8K	$9M	0.0%	Trim−408.6K
3	Izzy Englander Millennium Mgmt	441.8K	$8M	0.0%	Added+40.0K
4	Ken Griffin Citadel Advisors	408.4K	$7M	0.0%	Trim−152.9K
5	Ken Griffin Citadel Advisors	394.6K	$7M	0.0%	Trim−152.9K
6	Ken Griffin Citadel Advisors	240.4K	$4M	0.0%	Trim−152.9K
7	Wellington Management	202.6K	$3M	0.0%	Added+8.2K
8	T. Rowe Price	95.7K	$2M	0.0%	Added+6.2K
9	AQR Capital Management	22.8K	$392K	0.0%	Added+1.5K

Recent moves

20 transactions

TRIMD.E. Shaw & Co.
−250,236 · 2025Q4
ADDAQR Capital Management
+1,532 · 2025Q4
ADDT. Rowe Price
+6,217 · 2025Q4
TRIMKen Griffin (Citadel Advisors)
−152,876 · 2025Q4
ADDWellington Management
+8,170 · 2025Q4
TRIMTwo Sigma Investments
−408,557 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+39,997 · 2025Q4
SOLDRenaissance Technologies
−344,500 · 2025Q4
ADDWellington Management
+31,034 · 2025Q3
ADDIzzy Englander (Millennium Mgmt)
+132,393 · 2025Q3
ADDTwo Sigma Investments
+263,095 · 2025Q3
ADDAQR Capital Management
+7,444 · 2025Q3
ADDT. Rowe Price
+12,737 · 2025Q3
TRIMD.E. Shaw & Co.
−642,191 · 2025Q3
TRIMRenaissance Technologies
−38,200 · 2025Q3
ADDT. Rowe Price
+1,287 · 2025Q2
ADDTwo Sigma Investments
+564,580 · 2025Q2
TRIMIzzy Englander (Millennium Mgmt)
−45,831 · 2025Q2
TRIMD.E. Shaw & Co.
−291,102 · 2025Q2
ADDWellington Management
+27,411 · 2025Q2

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