Ticker · CUSIP 46333X108
Holders (tracked)
11
Combined shares
17,444,942
Combined value
$58.79M
Last close
$4.43
Quarter
2025Q4
Price · 1Y$4.43+3.70 (+506.85%)H $5.39 · L $0.57 · Avg Vol 2.7M
Tracked holders · last 8 quarters
+1 vs previous quarter over the last 8.
Price is +31.5% vs the avg quarter-end implied price across tracked holders.
SEC event timeline
16 events
- Two Sigma Investments added2026-02-17+318,694 shares · 2025Q4Position
- Ken Griffin (Citadel Advisors) trimmed2026-02-17−420,077 shares · 2025Q4Position
- D.E. Shaw & Co. trimmed2026-02-17−254,824 shares · 2025Q4Position
- Wellington Management opened position2026-02-17+503,942 shares · 2025Q4Position
- AQR Capital Management trimmed2026-02-17−655,004 shares · 2025Q4Position
- Izzy Englander (Millennium Mgmt) added2026-02-17+310,594 shares · 2025Q4Position
- T. Rowe Price added2026-02-17+19,185 shares · 2025Q4Position
- Renaissance Technologies trimmed2026-02-12−147,200 shares · 2025Q4Position
- −79,455 shares · 2025Q3Position
- AQR Capital Management trimmed2025-11-14−787,102 shares · 2025Q3Position
- Izzy Englander (Millennium Mgmt) added2025-11-14+153,787 shares · 2025Q3Position
- Two Sigma Investments trimmed2025-11-14−216,062 shares · 2025Q3Position
- D.E. Shaw & Co. trimmed2025-11-14−1,297,369 shares · 2025Q3Position
- T. Rowe Price trimmed2025-11-14−92,343 shares · 2025Q3Position
- Renaissance Technologies trimmed2025-11-13−53,996 shares · 2025Q3Position
- Norges Bank (Norway SWF) trimmed2025-11-12−998,811 shares · 2024Q3Position
Insider activity
No insider transactions in the last 30 days.
Follow-the-investor returns
If you'd copied each holder of IRWD…
Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.
| Investor | First in | Cost basis | Return | Position value today |
|---|---|---|---|---|
| D.E. Shaw & Co. | 2016Q1 | $1.19 | +273.1% | $520K |
| AQR Capital Management | 2016Q3 | $1.47 | +202.1% | $20.9M |
| Izzy Englander (Millennium Mgmt) | 2016Q1 | $2.48 | +78.4% | $2.5M |
| Ken Griffin (Citadel Advisors) | 2016Q2 | $3.24 | +36.6% | $992K |
| Ken Griffin (Citadel Advisors) | 2016Q2 | $3.24 | +36.6% | $992K |
| Ken Griffin (Citadel Advisors) | 2016Q2 | $3.24 | +36.6% | $992K |
| Two Sigma Investments | 2016Q1 | $3.73 | +18.6% | $12.6M |
| Wellington Management | 2016Q1 | $5.00 | -11.5% | $2.2M |
| T. Rowe Price | 2016Q1 | $6.23 | -28.9% | $440K |
| Renaissance Technologies | 2017Q1 | $9.28 | -52.2% | $36.3M |
| Ken Fisher (Fisher Asset Mgmt) | 2016Q1 | $11.32 | -60.9% | $44K |
Who moved on this name in 2025Q4
Position changes reported for the latest quarter, grouped by direction.
New positions1
- Wellington Management+503,942$1.7M
Added to3
- Two Sigma Investments+318,694$1.1M
- Izzy Englander (Millennium Mgmt)+310,594$1.0M
- T. Rowe Price+19,185$65
Trimmed4
- AQR Capital Management−655,004$2.2M
- Ken Griffin (Citadel Advisors)−420,077$1.4M
- D.E. Shaw & Co.−254,824$859K
- Renaissance Technologies−147,200$496K
Exited0
—
Institutional ownership over time
Distinct super-investors holding this ticker · combined dollar value, by quarter.
| Quarter | Holders | Combined value |
|---|---|---|
| 2022Q1 | 13 | $38.86B |
| 2022Q2 | 10 | $17.16B |
| 2022Q3 | 12 | $510.3M |
| 2022Q4 | 14 | $650.2M |
| 2023Q1 | 15 | $453.2M |
| 2023Q2 | 14 | $412.9M |
| 2023Q3 | 16 | $354.6M |
| 2023Q4 | 13 | $446.0M |
| 2024Q1 | 14 | $321.7M |
| 2024Q2 | 13 | $247.1M |
| 2024Q3 | 11 | $51.5M |
| 2024Q4 | 14 | $66.1M |
| 2025Q1 | 11 | $33.7M |
| 2025Q2 | 10 | $14.1M |
| 2025Q3 | 10 | $23.1M |
| 2025Q4 | 11 | $58.8M |
Who owns IRWD
11 super-investors · 2025Q4
Tracked stake
17.44M
shares
Combined value
$59M
% of shares outstanding
—
shares-out unknown
Quarter action mix
New1Added3Trim6Held1
| # | Manager | Shares | Value |
|---|---|---|---|
| 1 | Renaissance Technologies | 8.20M | $28M |
| 2 | AQR Capital Management | 4.72M | $16M |
| 3 | Two Sigma Investments | 2.85M | $10M |
| 4 | Izzy Englander Millennium Mgmt | 560.7K | $2M |
| 5 | Wellington Management | 503.9K | $2M |
| 6 | Ken Griffin Citadel Advisors | 224.0K | $755K |
| 7 | Ken Griffin Citadel Advisors | 134.1K | $452K |
| 8 | D.E. Shaw & Co. | 117.4K | $396K |
| 9 | T. Rowe Price | 99.4K | $335K |
| 10 | Ken Griffin Citadel Advisors | 13.7K | $46K |
| 11 | Ken Fisher Fisher Asset Mgmt | 10.0K | $34K |
Recent moves
20 transactions
- +310,594 · 2025Q4
- −655,004 · 2025Q4
- TRIMD.E. Shaw & Co.−254,824 · 2025Q4
- +19,185 · 2025Q4
- −420,077 · 2025Q4
- +318,694 · 2025Q4
- +503,942 · 2025Q4
- −147,200 · 2025Q4
- −79,455 · 2025Q3
- TRIMD.E. Shaw & Co.−1,297,369 · 2025Q3
- TRIMT. Rowe Price−92,343 · 2025Q3
- +153,787 · 2025Q3
- −787,102 · 2025Q3
- −216,062 · 2025Q3
- −53,996 · 2025Q3
- −998,811 · 2024Q3
- −1,532,565 · 2025Q2
- −6,263,350 · 2025Q2
- +1,523,377 · 2025Q2
- +1,559,915 · 2025Q2
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