Ticker · CUSIP 462222100

IONS

IONIS PHARMACEUTICALS INC
···Share
Holders (tracked)
18
Combined shares
15,908,591
Combined value
$1.26B
Last close
$75.71
Quarter
2025Q4
Price · 1Y$75.71+47.31 (+166.58%)H $86.50 · L $28.40 · Avg Vol 2.2M
$40.00$60.00$80.00VolJul 25Oct 25Jan 26Apr 26
Tracked holders · last 8 quarters
+4 vs previous quarter over the last 8.
18132024Q12025Q4
Price is -4.3% vs the avg quarter-end implied price across tracked holders.

SEC event timeline

29 events
  1. +3,661 shares · 2025Q4
    Position
  2. +11,947 shares · 2025Q4
    Position
  3. −267,429 shares · 2025Q4
    Position
  4. −298,135 shares · 2025Q4
    Position
  5. +1,082,703 shares · 2025Q4
    Position
  6. +11,000 shares · 2025Q4
    Position
  7. −686,308 shares · 2025Q4
    Position
  8. +28,200 shares · 2025Q4
    Position
  9. +258,155 shares · 2025Q4
    Position
  10. −328,486 shares · 2025Q4
    Position
  11. +24,128 shares · 2025Q4
    Position
  12. −263,107 shares · 2025Q4
    Position
  13. −208,247 shares · 2025Q4
    Position
  14. +320,160 shares · 2025Q4
    Position
  15. +135,405 shares · 2025Q4
    Position
  16. +630,938 shares · 2025Q3
    Position
  17. +6,815 shares · 2025Q3
    Position
  18. −1,869,957 shares · 2025Q3
    Position
  19. −292,647 shares · 2025Q3
    Position
  20. −212,424 shares · 2025Q3
    Position
  21. −396,388 shares · 2025Q3
    Position
  22. +243,035 shares · 2025Q3
    Position
  23. +25,000 shares · 2025Q3
    Position
  24. +43,578 shares · 2025Q3
    Position
  25. +216,000 shares · 2025Q3
    Position
  26. −450,254 shares · 2025Q3
    Position
  27. +6,210 shares · 2025Q3
    Position
  28. +1,007,820 shares · 2024Q3
    Position
  29. −269,103 shares · 2025Q3
    Position

Insider activity

No insider transactions in the last 30 days.
Follow-the-investor returns
If you'd copied each holder of IONS…
Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.
InvestorFirst inCost basisReturnPosition value today
Paul Tudor Jones (Tudor Investment)2016Q2$35.07+115.9%$277K
Steve Cohen (Point72)2016Q1$39.14+93.4%$1.1M
Steve Cohen (Point72)2016Q1$39.14+93.4%$1.1M
Izzy Englander (Millennium Mgmt)2016Q1$39.33+92.5%$7.1M
Wellington Management2016Q1$43.55+73.8%$474.0M
Cathie Wood (ARK Invest)2016Q4$45.67+65.8%$32.0M
Renaissance Technologies2016Q1$51.84+46.0%$16.9M
T. Rowe Price2016Q1$52.64+43.8%$226.2M
Two Sigma Investments2017Q2$55.09+37.4%$201.3M
D.E. Shaw & Co.2016Q1$64.57+17.3%$25.2M
Ray Dalio (Bridgewater Associates)2021Q2$66.50+13.9%$5.1M
Ron Baron (Baron Capital / BAMCO)2025Q3$69.60+8.8%$2.7M
AQR Capital Management2016Q1$70.55+7.3%$1.4M
Ken Griffin (Citadel Advisors)2016Q1$78.38-3.4%$5.2M
Ken Griffin (Citadel Advisors)2016Q1$78.38-3.4%$5.2M
Ken Griffin (Citadel Advisors)2016Q1$78.38-3.4%$5.2M
Ken Fisher (Fisher Asset Mgmt)2025Q3$78.51-3.6%$10.7M
Norges Bank (Norway SWF)2016Q1$3949.51-98.1%$24.2M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.
QuarterHoldersCombined value
2022Q1
13
$30.27B
2022Q2
15
$42.55B
2022Q3
14
$923.1M
2022Q4
15
$754.6M
2023Q1
14
$649.7M
2023Q2
15
$815.9M
2023Q3
13
$860.7M
2023Q4
13
$1.00B
2024Q1
13
$1.05B
2024Q2
15
$1.24B
2024Q3
13
$746.5M
2024Q4
12
$376.6M
2025Q1
12
$575.8M
2025Q2
12
$690.4M
2025Q3
14
$1.05B
2025Q4
18
$1.26B

Who owns IONS

18 super-investors · 2025Q4
Tracked stake
15.91M
shares
Combined value
$1.26B
% of shares outstanding
shares-out unknown
Quarter action mix
New4Added6Trim8
#ManagerSharesValue
1Wellington Management6.26M$495M
2T. Rowe Price2.99M$236M
3Two Sigma Investments2.66M$210M
4Ken Griffin
Citadel Advisors
2.13M$169M
5Cathie Wood
ARK Invest
423.0K$33M
6D.E. Shaw & Co.332.8K$26M
7Norges Bank
Norway SWF
320.2K$25M
8Renaissance Technologies223.6K$18M
9Ken Fisher
Fisher Asset Mgmt
141.6K$11M
10Ken Griffin
Citadel Advisors
109.4K$9M
11Izzy Englander
Millennium Mgmt
93.3K$7M
12Ken Griffin
Citadel Advisors
69.0K$5M
13Ray Dalio
Bridgewater Associates
67.7K$5M
14Ron Baron
Baron Capital / BAMCO
36.0K$3M
15AQR Capital Management18.8K$1M
16Steve Cohen
Point72
14.1K$1M
17Steve Cohen
Point72
14.1K$1M
18Paul Tudor Jones
Tudor Investment
3.7K$290K

Recent moves

20 transactions
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