Ticker · CUSIP 427746102

HRTX

HERON THERAPEUTICS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

15,678,640

Combined value

$20.38M

Last close

$1.00

Quarter

2025Q4

Price is -23.1% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$1.00-0.84 (-45.65%)H $2.42 · L $0.75 · Avg Vol 1.8M

Tracked holders · last 8 quarters

Flat over the last 8 quarters.

SEC event timeline

14 events

Two Sigma Investments added2026-02-17
+307,230 shares · 2025Q4
Position
AQR Capital Management trimmed2026-02-17
−1,560,389 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) trimmed2026-02-17
−613,412 shares · 2025Q4
Position
D.E. Shaw & Co. trimmed2026-02-17
−83,852 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+6,921,405 shares · 2025Q4
Position
Wellington Management exited2026-02-17
−525,774 shares · 2025Q4
Position
Renaissance Technologies trimmed2026-02-12
−939,099 shares · 2025Q4
Position
AQR Capital Management added2025-11-14
+1,874,940 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−243,834 shares · 2025Q3
Position
Two Sigma Investments trimmed2025-11-14
−248,303 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−111,807 shares · 2025Q3
Position
T. Rowe Price trimmed2025-11-14
−2,805,039 shares · 2025Q3
Position
Wellington Management added2025-11-14
+32,691 shares · 2025Q3
Position
Renaissance Technologies added2025-11-13
+165,660 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for HRTX →

Follow-the-investor returns

If you'd copied each holder of HRTX…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
AQR Capital Management	2019Q1	$1.30	-23.0%	$376K
Ken Griffin (Citadel Advisors)	2016Q1	$1.30	-23.1%	$2.1M
Ken Griffin (Citadel Advisors)	2016Q1	$1.30	-23.1%	$2.1M
Ken Griffin (Citadel Advisors)	2016Q1	$1.30	-23.1%	$2.1M
Izzy Englander (Millennium Mgmt)	2016Q1	$1.33	-24.9%	$7.2M
Renaissance Technologies	2017Q4	$2.11	-52.6%	$1.9M
T. Rowe Price	2017Q2	$2.27	-55.9%	$77K
Two Sigma Investments	2018Q2	$2.68	-62.7%	$1000K
D.E. Shaw & Co.	2016Q1	$3.97	-74.8%	$3.0M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions0

—

Added to2

Izzy Englander (Millennium Mgmt)
+6,921,405
$9.0M
Two Sigma Investments
+307,230
$399K

Trimmed4

AQR Capital Management
−1,560,389
$2.0M
Renaissance Technologies
−939,099
$1.2M
Ken Griffin (Citadel Advisors)
−613,412
$797K
D.E. Shaw & Co.
−83,852
$109K

Exited1

Wellington Management
−525,774
$662K

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	12	14,571,334	$4.79B	—
2022Q2	14	12,647,937	$2.51B	+2
2022Q3	13	13,830,462	$58.4M	-1
2022Q4	15	18,176,564	$45.4M	+2
2023Q1	15	14,266,940	$21.5M	—
2023Q2	12	10,937,929	$12.7M	-3
2023Q3	9	8,911,275	$9.2M	-3
2023Q4	8	10,838,274	$18.4M	-1
2024Q1	11	14,051,405	$38.9M	+3
2024Q2	11	18,497,414	$64.7M	—
2024Q3	10	11,838,314	$23.6M	-1
2024Q4	9	9,516,651	$14.6M	-1
2025Q1	11	16,555,357	$36.4M	+2
2025Q2	9	13,021,903	$27.0M	-2
2025Q3	9	12,191,431	$15.4M	—
2025Q4	9	15,678,640	$20.4M	—

Who owns HRTX

9 super-investors · 2025Q4

Tracked stake

15.68M

Combined value

$20M

% of shares outstanding

—

shares-out unknown

Quarter action mix

Added2Trim6Held1

#	Manager	Shares	Value	% of book	Last action
1	Izzy Englander Millennium Mgmt	7.17M	$9M	0.0%	Added+6.92M
2	D.E. Shaw & Co.	3.00M	$4M	0.0%	Trim−83.9K
3	Ken Griffin Citadel Advisors	2.10M	$3M	0.0%	Trim−613.4K
4	Renaissance Technologies	1.92M	$2M	0.0%	Trim−939.1K
5	Two Sigma Investments	999.5K	$1M	0.0%	Added+307.2K
6	AQR Capital Management	376.3K	$489K	0.0%	Trim−1.56M
7	T. Rowe Price	76.6K	$100K	0.0%	Held
8	Ken Griffin Citadel Advisors	23.3K	$30K	0.0%	Trim−613.4K
9	Ken Griffin Citadel Advisors	17.4K	$23K	0.0%	Trim−613.4K

Recent moves

20 transactions

ADDIzzy Englander (Millennium Mgmt)
+6,921,405 · 2025Q4
ADDTwo Sigma Investments
+307,230 · 2025Q4
SOLDWellington Management
−525,774 · 2025Q4
TRIMKen Griffin (Citadel Advisors)
−613,412 · 2025Q4
TRIMD.E. Shaw & Co.
−83,852 · 2025Q4
TRIMAQR Capital Management
−1,560,389 · 2025Q4
TRIMRenaissance Technologies
−939,099 · 2025Q4
TRIMTwo Sigma Investments
−248,303 · 2025Q3
TRIMD.E. Shaw & Co.
−111,807 · 2025Q3
TRIMT. Rowe Price
−2,805,039 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−243,834 · 2025Q3
ADDAQR Capital Management
+1,874,940 · 2025Q3
ADDWellington Management
+32,691 · 2025Q3
ADDRenaissance Technologies
+165,660 · 2025Q3
ADDD.E. Shaw & Co.
+214,102 · 2025Q2
TRIMT. Rowe Price
−122,999 · 2025Q2
SOLDSteve Cohen (Point72)
−4,775,877 · 2025Q2
TRIMIzzy Englander (Millennium Mgmt)
−902,948 · 2025Q2
TRIMTwo Sigma Investments
−112,399 · 2025Q2
ADDWellington Management
+5,841 · 2025Q2

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