Ticker · CUSIP 12529R107

CCCC

C4 THERAPEUTICS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

14,304,367

Combined value

$27.32M

Last close

$2.92

Quarter

2025Q4

Price is +52.9% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$2.92+1.67 (+133.60%)H $3.59 · L $1.25 · Avg Vol 1.9M

Position opened

Tracked holders · last 8 quarters

+1 vs previous quarter over the last 8.

SEC event timeline

11 events

D.E. Shaw & Co. added2026-02-17
+41,016 shares · 2025Q4
Position
Two Sigma Investments added2026-02-17
+674,877 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) trimmed2026-02-17
−33,641 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) trimmed2026-02-17
−745,256 shares · 2025Q4
Position
Steve Cohen (Point72) opened position2026-02-17
+9,439,328 shares · 2025Q4
Position
Renaissance Technologies added2026-02-12
+665,630 shares · 2025Q4
Position
AQR Capital Management exited2025-11-14
−383,789 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) added2025-11-14
+832,883 shares · 2025Q3
Position
Two Sigma Investments added2025-11-14
+151,127 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−77,612 shares · 2025Q3
Position
Renaissance Technologies trimmed2025-11-13
−156,238 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for CCCC →

Follow-the-investor returns

If you'd copied each holder of CCCC…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Renaissance Technologies	2021Q4	$1.92	+52.3%	$4.7M
Steve Cohen (Point72)	2021Q2	$1.99	+46.9%	$27.6M
Izzy Englander (Millennium Mgmt)	2020Q4	$2.19	+33.3%	$3.5M
Ken Griffin (Citadel Advisors)	2020Q4	$2.33	+25.2%	$35K
Ken Griffin (Citadel Advisors)	2020Q4	$2.33	+25.2%	$35K
Ken Griffin (Citadel Advisors)	2020Q4	$2.33	+25.2%	$35K
D.E. Shaw & Co.	2020Q4	$2.40	+21.4%	$154K
Two Sigma Investments	2021Q2	$3.59	-18.7%	$4.4M
T. Rowe Price	2020Q4	$9.72	-70.0%	$36K

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions1

Steve Cohen (Point72)
+9,439,328
$18.0M

Added to3

Two Sigma Investments
+674,877
$1.3M
Renaissance Technologies
+665,630
$1.3M
D.E. Shaw & Co.
+41,016
$78K

Trimmed2

Izzy Englander (Millennium Mgmt)
−745,256
$1.4M
Ken Griffin (Citadel Advisors)
−33,641
$64K

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	10	9,517,151	$230.9M	—
2022Q2	10	8,768,587	$66.1M	—
2022Q3	10	7,146,562	$62.7M	—
2022Q4	10	7,585,595	$44.8M	—
2023Q1	13	8,847,205	$27.8M	+3
2023Q2	11	9,917,764	$27.3M	-2
2023Q3	12	8,186,379	$15.2M	+1
2023Q4	10	8,006,841	$45.2M	-2
2024Q1	10	6,819,453	$55.7M	—
2024Q2	12	8,072,012	$37.3M	+2
2024Q3	10	3,025,976	$17.2M	-2
2024Q4	10	1,605,754	$5.8M	—
2025Q1	7	1,289,805	$2.1M	-3
2025Q2	6	3,363,793	$4.8M	-1
2025Q3	8	4,356,013	$9.7M	+2
2025Q4	9	14,304,367	$27.3M	+1

Who owns CCCC

9 super-investors · 2025Q4

Tracked stake

14.30M

Combined value

$27M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New1Added3Trim4Held1

#	Manager	Shares	Value	% of book	Last action
1	Steve Cohen Point72	9.44M	$18M	0.0%	New+9.44M
2	Renaissance Technologies	1.60M	$3M	0.0%	Added+665.6K
3	Two Sigma Investments	1.51M	$3M	0.0%	Added+674.9K
4	Izzy Englander Millennium Mgmt	1.19M	$2M	0.0%	Trim−745.3K
5	Ken Griffin Citadel Advisors	447.8K	$855K	0.0%	Trim−33.6K
6	D.E. Shaw & Co.	52.9K	$101K	0.0%	Added+41.0K
7	Ken Griffin Citadel Advisors	38.7K	$74K	0.0%	Trim−33.6K
8	T. Rowe Price	12.4K	$24K	0.0%	Held
9	Ken Griffin Citadel Advisors	12.1K	$23K	0.0%	Trim−33.6K

Recent moves

20 transactions

ADDD.E. Shaw & Co.
+41,016 · 2025Q4
TRIMIzzy Englander (Millennium Mgmt)
−745,256 · 2025Q4
ADDTwo Sigma Investments
+674,877 · 2025Q4
TRIMKen Griffin (Citadel Advisors)
−33,641 · 2025Q4
NEWSteve Cohen (Point72)
+9,439,328 · 2025Q4
ADDRenaissance Technologies
+665,630 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+832,883 · 2025Q3
SOLDAQR Capital Management
−383,789 · 2025Q3
TRIMD.E. Shaw & Co.
−77,612 · 2025Q3
ADDTwo Sigma Investments
+151,127 · 2025Q3
TRIMRenaissance Technologies
−156,238 · 2025Q3
ADDD.E. Shaw & Co.
+10,200 · 2025Q2
ADDAQR Capital Management
+243,257 · 2025Q2
ADDIzzy Englander (Millennium Mgmt)
+1,035,445 · 2025Q2
SOLDSteve Cohen (Point72)
−236,855 · 2025Q2
ADDTwo Sigma Investments
+168,996 · 2025Q2
TRIMT. Rowe Price
−25,743 · 2025Q2
ADDRenaissance Technologies
+878,688 · 2025Q2
ADDSteve Cohen (Point72)
+40,389 · 2025Q1
TRIMIzzy Englander (Millennium Mgmt)
−294,228 · 2025Q1

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