Ticker · CUSIP 00847X104

AGIO

AGIOS PHARMACEUTICALS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

5,725,260

Combined value

$155.84M

Last close

$35.14

Quarter

2025Q4

Price is +29.1% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$35.14+7.48 (+27.04%)H $45.49 · L $22.34 · Avg Vol 962K

Congress buy

Tracked holders · last 8 quarters

+3 vs previous quarter over the last 8.

SEC event timeline

20 events

Ken Griffin (Citadel Advisors) added2026-02-17
+856,986 shares · 2025Q4
Position
D.E. Shaw & Co. added2026-02-17
+1,469,437 shares · 2025Q4
Position
Two Sigma Investments added2026-02-17
+240,527 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+393,218 shares · 2025Q4
Position
Steve Cohen (Point72) added2026-02-17
+193,493 shares · 2025Q4
Position
T. Rowe Price trimmed2026-02-17
−1,019,052 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) opened position2026-02-17
+61,345 shares · 2025Q4
Position
Wellington Management trimmed2026-02-17
−1,873,590 shares · 2025Q4
Position
AQR Capital Management trimmed2026-02-17
−63,709 shares · 2025Q4
Position
Ken Fisher (Fisher Asset Mgmt) exited2026-02-09
−870,145 shares · 2025Q4
Position
AQR Capital Management trimmed2025-11-14
−5,261 shares · 2025Q3
Position
Steve Cohen (Point72) opened position2025-11-14
+6,507 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−295,154 shares · 2025Q3
Position
Two Sigma Investments opened position2025-11-14
+59,629 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−228,453 shares · 2025Q3
Position
T. Rowe Price trimmed2025-11-14
−617,311 shares · 2025Q3
Position
Wellington Management added2025-11-14
+2,049,287 shares · 2025Q3
Position
Norges Bank (Norway SWF) exited2025-11-13
−6,756 shares · 2025Q3
Position
Ken Fisher (Fisher Asset Mgmt) trimmed2025-11-12
−7,395 shares · 2025Q3
Position
Norges Bank (Norway SWF) trimmed2025-11-12
−66,879 shares · 2024Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for AGIO →

Follow-the-investor returns

If you'd copied each holder of AGIO…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Izzy Englander (Millennium Mgmt)	2016Q1	$27.29	+28.7%	$14.0M
Izzy Englander (Millennium Mgmt)	2016Q1	$27.29	+28.7%	$14.0M
D.E. Shaw & Co.	2016Q1	$27.36	+28.4%	$64.6M
D.E. Shaw & Co.	2016Q1	$27.36	+28.4%	$64.6M
Ken Griffin (Citadel Advisors)	2016Q3	$27.38	+28.3%	$7.4M
Ken Griffin (Citadel Advisors)	2016Q3	$27.38	+28.3%	$7.4M
Ken Griffin (Citadel Advisors)	2016Q3	$27.38	+28.3%	$7.4M
Paul Tudor Jones (Tudor Investment)	2019Q2	$27.63	+27.2%	$411K
Paul Tudor Jones (Tudor Investment)	2019Q2	$27.63	+27.2%	$411K
Steve Cohen (Point72)	2016Q4	$27.76	+26.6%	$7.0M
Two Sigma Investments	2017Q3	$28.72	+22.3%	$10.5M
AQR Capital Management	2016Q2	$35.76	-1.7%	$981K
Wellington Management	2016Q1	$39.09	-10.1%	$21.0M
T. Rowe Price	2016Q1	$46.73	-24.8%	$22.4M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions1

Paul Tudor Jones (Tudor Investment)
+61,345
$1.7M

Added to5

D.E. Shaw & Co.
+1,469,437
$40.0M
Ken Griffin (Citadel Advisors)
+856,986
$23.3M
Izzy Englander (Millennium Mgmt)
+393,218
$10.7M
Two Sigma Investments
+240,527
$6.5M
Steve Cohen (Point72)
+193,493
$5.3M

Trimmed3

Wellington Management
−1,873,590
$51.0M
AQR Capital Management
−63,709
$1.7M
T. Rowe Price
−1,019,052
$28K

Exited1

Ken Fisher (Fisher Asset Mgmt)
−870,145
$34.9M

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	12	13,854,085	$14.82B	—
2022Q2	12	13,902,089	$10.84B	—
2022Q3	13	13,384,414	$378.5M	+1
2022Q4	12	13,430,246	$377.1M	-1
2023Q1	12	13,434,834	$308.6M	—
2023Q2	11	13,436,295	$380.5M	-1
2023Q3	9	7,963,194	$197.1M	-2
2023Q4	11	8,857,002	$197.2M	+2
2024Q1	13	8,955,207	$261.9M	+2
2024Q2	11	9,527,751	$410.8M	-2
2024Q3	11	4,831,155	$214.6M	—
2024Q4	11	5,717,727	$187.9M	—
2025Q1	9	4,879,435	$143.0M	-2
2025Q2	10	5,719,545	$190.2M	+1
2025Q3	11	6,134,050	$246.1M	+1
2025Q4	14	5,725,260	$155.8M	+3

Congress members trading this stock

Date	Member	Type	Amount range	Filing
2026-03-03	Gilbert Cisneros	Buy	$1K – $15K	PDF ↗
2025-12-11	Gilbert Cisneros	Buy	$1K – $15K	PDF ↗
2025-04-17	Gilbert Cisneros	Buy	$1K – $15K	PDF ↗
2025-01-29	Gilbert Cisneros	Buy	$1K – $15K	PDF ↗

Who owns AGIO

14 super-investors · 2025Q4

Tracked stake

5.73M

Combined value

$156M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New2Added9Trim3

#	Manager	Shares	Value	% of book	Last action
1	D.E. Shaw & Co.	1.84M	$50M	0.0%	Added+1.47M
2	Ken Griffin Citadel Advisors	1.35M	$37M	0.0%	Added+857.0K
3	T. Rowe Price	637.9K	$17M	0.0%	Trim−1.02M
4	Wellington Management	597.8K	$16M	0.0%	Trim−1.87M
5	Izzy Englander Millennium Mgmt	398.3K	$11M	0.0%	Added+393.2K
6	Two Sigma Investments	300.2K	$8M	0.0%	Added+240.5K
7	Ken Griffin Citadel Advisors	209.7K	$6M	0.0%	Added+857.0K
8	Steve Cohen Point72	200.0K	$5M	0.0%	Added+193.5K
9	Paul Tudor Jones Tudor Investment	61.3K	$2M	0.0%	New+61.3K
10	Ken Griffin Citadel Advisors	50.2K	$1M	0.0%	Added+857.0K
11	AQR Capital Management	27.9K	$754K	0.0%	Trim−63.7K
12	D.E. Shaw & Co.	24.1K	$656K	0.0%	Added+1.47M
13	Izzy Englander Millennium Mgmt	20.0K	$544K	0.0%	Added+393.2K
14	Paul Tudor Jones Tudor Investment	11.7K	$318K	0.0%	New+61.3K

Recent moves

20 transactions

ADDIzzy Englander (Millennium Mgmt)
+393,218 · 2025Q4
TRIMAQR Capital Management
−63,709 · 2025Q4
ADDD.E. Shaw & Co.
+1,469,437 · 2025Q4
TRIMT. Rowe Price
−1,019,052 · 2025Q4
TRIMWellington Management
−1,873,590 · 2025Q4
ADDSteve Cohen (Point72)
+193,493 · 2025Q4
ADDTwo Sigma Investments
+240,527 · 2025Q4
NEWPaul Tudor Jones (Tudor Investment)
+61,345 · 2025Q4
ADDKen Griffin (Citadel Advisors)
+856,986 · 2025Q4
SOLDKen Fisher (Fisher Asset Mgmt)
−870,145 · 2025Q4
NEWTwo Sigma Investments
+59,629 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−295,154 · 2025Q3
ADDWellington Management
+2,049,287 · 2025Q3
NEWSteve Cohen (Point72)
+6,507 · 2025Q3
TRIMT. Rowe Price
−617,311 · 2025Q3
TRIMAQR Capital Management
−5,261 · 2025Q3
TRIMD.E. Shaw & Co.
−228,453 · 2025Q3
SOLDNorges Bank (Norway SWF)
−6,756 · 2025Q3
TRIMNorges Bank (Norway SWF)
−66,879 · 2024Q3
TRIMKen Fisher (Fisher Asset Mgmt)
−7,395 · 2025Q3

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