Ticker · CUSIP 00773J202

SYRE

AEGLEA BIOTHERAPEUTICS INC
···Share
Holders (tracked)
8
Combined shares
4,006,462
Combined value
$131.25M
Last close
$73.01
Quarter
2025Q4
Price · 1Y$73.01+60.34 (+476.24%)H $73.01 · L $12.51 · Avg Vol 756K
Position opened
$20.00$40.00$60.00VolJul 25Oct 25Jan 26Apr 26
Tracked holders · last 8 quarters
+4 vs previous quarter over the last 8.
882024Q12025Q4
Price is +122.9% vs the avg quarter-end implied price across tracked holders.

SEC event timeline

13 events
  1. +63,904 shares · 2025Q4
    Position
  2. −332,005 shares · 2025Q4
    Position
  3. +662,351 shares · 2025Q4
    Position
  4. +981,262 shares · 2025Q4
    Position
  5. +10,127 shares · 2025Q4
    Position
  6. −91,028 shares · 2025Q4
    Position
  7. +773 shares · 2025Q4
    Position
  8. +408,199 shares · 2025Q3
    Position
  9. −309,861 shares · 2025Q3
    Position
  10. +126,834 shares · 2025Q3
    Position
  11. −926 shares · 2025Q3
    Position
  12. −30,936 shares · 2025Q3
    Position
  13. −70,843 shares · 2024Q3
    Position

Insider activity

No insider transactions in the last 30 days.
Follow-the-investor returns
If you'd copied each holder of SYRE…
Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.
InvestorFirst inCost basisReturnPosition value today
Izzy Englander (Millennium Mgmt)2023Q3$22.72+221.3%$5.6M
T. Rowe Price2024Q1$27.13+169.1%$117.0M
Wellington Management2023Q3$27.33+167.2%$113.1M
Paul Tudor Jones (Tudor Investment)2024Q3$29.41+148.2%$739K
AQR Capital Management2024Q3$29.56+147.0%$1.3M
Ken Griffin (Citadel Advisors)2023Q3$31.53+131.5%$1.8M
Ken Griffin (Citadel Advisors)2023Q3$31.53+131.5%$1.8M
Steve Cohen (Point72)2025Q4$32.76+122.9%$48.4M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.
Added to2
Trimmed2
Exited0

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.
QuarterHoldersCombined value
2023Q3
7
$5.9M
2023Q4
7
$16.8M
2024Q1
8
$97.4M
2024Q2
9
$104.5M
2024Q3
9
$84.3M
2024Q4
7
$47.1M
2025Q1
6
$34.0M
2025Q2
4
$37.3M
2025Q3
4
$45.0M
2025Q4
8
$131.3M

Who owns SYRE

8 super-investors · 2025Q4
Tracked stake
4.01M
shares
Combined value
$131M
% of shares outstanding
shares-out unknown
Quarter action mix
New4Added2Trim2
#ManagerSharesValue
1T. Rowe Price1.60M$52M
2Wellington Management1.55M$51M
3Steve Cohen
Point72
662.4K$22M
4Izzy Englander
Millennium Mgmt
76.2K$2M
5Ken Griffin
Citadel Advisors
63.9K$2M
6Ken Griffin
Citadel Advisors
24.9K$816K
7AQR Capital Management17.8K$584K
8Paul Tudor Jones
Tudor Investment
10.1K$332K

Recent moves

20 transactions
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